MuScle-logoMuScle - Molecule ID BK022

geneAKAP7, AKAP18, AKAP15
nameProtein kinase A anchoring protein 7 isoform gamma
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AKA7G_HUMAN|AKA7A_HUMANQ9P0M2ENSG000001185079465Hs.486483604693

Functions and classifications

GOC:cytosol, C:nucleus, F:catalytic activity, F:nucleotide binding, F:protein kinase A binding, P:metabolic process, C:apical plasma membrane, C:lateral plasma membrane, P:cellular response to cAMP, P:intracellular signal transduction, P:ion transport, P:positive regulation of delayed rectifier potassium channel activity, P:positive regulation of potassium ion transmembrane transport, P:protein localization, P:regulation of action potential, P:regulation of membrane repolarization, F:kinase activity, C:exocytic vesicle, C:protein complex, C:sarcoplasmic reticulum, C:T-tubule, F:AMP binding, P:regulation of protein kinase A signaling cascade, P:RNA metabolic process, C:intracellular
UniProtAlternative splicing, Complete proteome, Cytoplasm, Nucleotide-binding, Nucleus, Polymorphism, Reference proteome, Cell membrane, Lipoprotein, Membrane, Myristate, Palmitate, Kinase, Transferase
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)1.326.26E-0420136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.750.0066565820136355
Exp21216829Homo sapiens8BloodCD8+RRMS_(CD8+) (Multiple sclerosis)0.360.0291456821216829
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.862.91E-0322021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.321.25E-0322252466

Compile date 09-07-2016© MuScle project