MuScle-logoMuScle - Molecule ID BK020

geneADORA3, UNQ1931/PRO4406, UNQ1931
nameAdenosine A3 receptor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AA3R_HUMAN|AA3RB_HUMANP33765ENSG00000121933140Hs.281342600445

Functions and classifications

GOC:integral component of plasma membrane, C:mast cell granule, F:G-protein coupled adenosine receptor activity, P:activation of adenylate cyclase activity, P:histamine secretion by mast cell, P:inflammatory response, P:positive regulation of calcium-mediated signaling, P:positive regulation of inflammatory response, P:positive regulation of leukocyte migration, P:positive regulation of mast cell degranulation, P:positive regulation of mucus secretion, P:positive regulation of phosphatidylinositol 3-kinase signaling, P:regulation of heart contraction, P:signal transduction, C:integral component of membrane, C:plasma membrane, C:integral to plasma membrane, P:positive regulation of phosphatidylinositol 3-kinase cascade, C:integral to membrane
UniProt3D-structure, Alternative splicing, Cell membrane, Complete proteome, Disulfide bond, G-protein coupled receptor, Glycoprotein, Lipoprotein, Membrane, Palmitate, Phosphoprotein, Polymorphism, Receptor, Reference proteome, Transducer, Transmembrane, Transmembrane helix
PADBRCP: receptor

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)1.663.71E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)1.620.0303553620136355
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_3_month_follow-up) (Multiple sclerosis)1.720.0321948421886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.181.73E-0222021740
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)0.842.05E-0222252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.738.27E-0622252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.846.45E-0322252466
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)0.390.0133421522491253

Compile date 09-07-2016© MuScle project