MuScle-logoMuScle - Molecule ID BJ830

geneADARB1, hRED1, ADAR2d
nameRNA-specific adenosine deaminase B1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
RED1_HUMANP78563ENSG00000197381104Hs.474018601218

Functions and classifications

GOC:nucleolus, C:nucleoplasm, C:nucleus, F:adenosine deaminase activity, F:double-stranded RNA adenosine deaminase activity, F:double-stranded RNA binding, F:metal ion binding, F:mRNA binding, F:RNA binding, P:adenosine to inosine editing, P:base conversion or substitution editing, P:defense response to virus, P:gene expression, P:innate immune response, P:mRNA modification, P:mRNA processing, P:negative regulation of cell migration, P:negative regulation of cell proliferation, P:negative regulation of protein kinase activity by regulation of protein phosphorylation, P:positive regulation of viral genome replication, P:regulation of cell cycle, P:RNA processing, C:intracellular
UniProt3D-structure, Alternative splicing, Antiviral defense, Complete proteome, Hydrolase, Immunity, Innate immunity, Metal-binding, mRNA processing, Nucleus, Phosphoprotein, Reference proteome, Repeat, RNA-binding, Zinc
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.675.41E-0320136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.730.0243198720136355
Exp21216829Homo sapiens8BloodCD8+RRMS_(CD8+) (Multiple sclerosis)0.320.0116411721216829
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.732.55E-0422021740
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)1.113.14E-0222252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.851.36E-0222252466
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)1.750.0297902422491253

Compile date 09-07-2016© MuScle project