MuScle-logoMuScle - Molecule ID BJ420

geneAPLN, APEL
nameApelin precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
APEL_HUMANQ9ULZ1ENSG000001713888862Hs.303084300297

Functions and classifications

GOC:extracellular region, C:extracellular space, C:perinuclear region of cytoplasm, F:receptor binding, P:drinking behavior, P:immune response, P:lactation, P:negative regulation of blood pressure, P:negative regulation of vasoconstriction, P:positive regulation of cell proliferation, P:positive regulation of corticotropin secretion, P:positive regulation of corticotropin-releasing hormone secretion, P:positive regulation of heat generation, P:positive regulation of phosphorylation, P:positive regulation of vasodilation, P:regulation of respiratory gaseous exchange, P:regulation of the force of heart contraction, P:signal transduction
UniProtCleavage on pair of basic residues, Complete proteome, Hormone, Reference proteome, Secreted, Signal
PADBSIG: signalling

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)1.353.62E-0217467740
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)1.280.0158673720136355
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.783.53E-0422252466

Compile date 09-07-2016© MuScle project