MuScle-logoMuScle - Molecule ID BJ404

geneAES, GRG
nameGRG protein
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AES_HUMANQ08117ENSG00000104964166Hs.515053600188

Functions and classifications

GOC:nucleus, F:transcription corepressor activity, P:cellular response to extracellular stimulus, P:negative regulation of canonical Wnt signaling pathway, P:negative regulation of protein binding, P:negative regulation of response to cytokine stimulus, P:negative regulation of transcription from RNA polymerase II promoter, P:organ morphogenesis, P:positive regulation of anoikis, P:regulation of growth, P:response to interleukin-1, P:skeletal system development, P:transcription, DNA-templated, P:Wnt signaling pathway, P:negative regulation of canonical Wnt receptor signaling pathway, P:transcription, DNA-dependent, P:Wnt receptor signaling pathway"
UniProtAlternative splicing, Complete proteome, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Repressor, Transcription, Transcription regulation, Ubl conjugation, Wnt signaling pathway
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.850.0210990920136355
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)0.684.66E-0222252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.522.13E-0222252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.871.50E-0322252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.892.19E-0522252466

Compile date 09-07-2016© MuScle project