MuScle-logoMuScle - Molecule ID BG485

geneACAT1, ACAT, MAT
nameAcetyl-CoA acetyltransferase, mitochondrial precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
THIL_HUMANP24752ENSG0000007523938Hs.232375203750, 607809

Functions and classifications

GOC:mitochondrial inner membrane, C:mitochondrial matrix, F:acetyl-CoA C-acetyltransferase activity, F:coenzyme binding, F:metal ion binding, P:adipose tissue development, P:brain development, P:branched-chain amino acid catabolic process, P:cellular lipid metabolic process, P:cellular nitrogen compound metabolic process, P:ketone body biosynthetic process, P:ketone body catabolic process, P:liver development, P:metanephric proximal convoluted tubule development, P:protein homooligomerization, P:response to hormone, P:response to organic cyclic compound, P:response to starvation, "F:transferase activity, transferring acyl groups other than amino-acyl groups", "C:mitochondrion, F:transferase activity, transferring acyl groups other than amino-acyl groups", P:response to hormone stimulus
UniProt3D-structure, Acetylation, Acyltransferase, Complete proteome, Direct protein sequencing, Disease mutation, Metal-binding, Mitochondrion, Polymorphism, Potassium, Reference proteome, Transferase, Transit peptide
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.144.69E-0222021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.405.34E-0322252466

Compile date 09-07-2016© MuScle project