MuScle-logoMuScle - Molecule ID BG484

geneACAA1, ACAA, PTHIO
name3-ketoacyl-CoA thiolase, peroxisomal precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
THIK_HUMANP09110ENSG0000006097130Hs.643487604054

Functions and classifications

GOC:peroxisomal matrix, F:acetyl-CoA C-acyltransferase activity, F:palmitoyl-CoA oxidase activity, P:alpha-linolenic acid metabolic process, P:bile acid metabolic process, P:fatty acid beta-oxidation using acyl-CoA oxidase, P:very long-chain fatty acid metabolic process, "F:transferase activity, transferring acyl groups other than amino-acyl groups"
UniProt3D-structure, Acyltransferase, Alternative splicing, Complete proteome, Fatty acid metabolism, Lipid metabolism, Peroxisome, Phosphoprotein, Polymorphism, Reference proteome, Transferase, Transit peptide
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)0.820.01755621886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.830.040212221886806
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)0.671.59E-0222252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.494.00E-0922252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.608.91E-0422252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.089.23E-0323895517

Compile date 09-07-2016© MuScle project