MuScle-logoMuScle - Molecule ID BG407

geneBRF1, BRF, GTF3B
nameTranscription factor IIIB 90 kDa subunit
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
TF3B_HUMANQ92994ENSG000001850242972Hs.424484604902

Functions and classifications

GOC:nucleoplasm, C:transcription factor TFIIIB complex, F:zinc ion binding, P:positive regulation of transcription, DNA-templated, P:regulation of mRNA stability, P:rRNA transcription, P:transcription initiation from RNA polymerase III promoter, P:tRNA transcription, "F:zinc ion binding, P:DNA-templated transcription, initiation, P:regulation of transcription, DNA-templated", "C:nucleus, F:translation initiation factor activity, P:positive regulation of transcription, DNA-templated", P:regulation of mRNA stability", F:metal ion binding, P:DNA-dependent transcription, initiation, P:positive regulation of transcription, DNA-dependent, P:regulation of transcription, DNA-dependent", P:positive regulation of transcription, DNA-dependent"
UniProtActivator, Alternative splicing, Complete proteome, Direct protein sequencing, Metal-binding, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Transcription, Transcription regulation, Zinc, Zinc-finger, Initiation factor, Protein biosynthesis
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.780.0188363820136355
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)0.720.035190422252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.601.24E-0622252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)2.043.94E-0822252466
Exp22491253Homo sapiens7Blood RRMS_(Low_Sema4A) (Multiple sclerosis)0.270.000295422491253
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.064.17E-0223895517

Compile date 09-07-2016© MuScle project