MuScle-logoMuScle - Molecule ID BF872

geneAARS2, AARSL
nameProbable alanyl-tRNA synthetase, mitochondrial precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
SYAM_HUMANQ5JTZ9ENSG0000012460857505Hs.158381612035, 614096

Functions and classifications

GOC:mitochondrion, F:alanine-tRNA ligase activity, F:ATP binding, F:metal ion binding, F:tRNA binding, P:mitochondrial alanyl-tRNA aminoacylation, P:mitochondrial respiratory chain complex assembly, C:cytoplasm, F:nucleotide binding
UniProtAminoacyl-tRNA synthetase, ATP-binding, Cardiomyopathy, Complete proteome, Disease mutation, Ligase, Metal-binding, Mitochondrion, Nucleotide-binding, Polymorphism, Protein biosynthesis, Reference proteome, RNA-binding, Transit peptide, tRNA-binding, Zinc
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.900.0497014120136355
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.611.01E-0622252466
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)1.560.04575322491253
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.147.91E-0323895517

Compile date 09-07-2016© MuScle project