MuScle-logoMuScle - Molecule ID BF871

geneAARS
nameAlanyl-tRNA synthetase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
SYAC_HUMANP49588ENSG0000009086116Hs.315137601065, 613287

Functions and classifications

GOC:cytosol, F:alanine-tRNA ligase activity, F:amino acid binding, F:aminoacyl-tRNA editing activity, F:ATP binding, F:metal ion binding, F:tRNA binding, P:alanyl-tRNA aminoacylation, P:cerebellar Purkinje cell layer development, P:endoplasmic reticulum unfolded protein response, P:hair follicle development, P:negative regulation of neuron apoptotic process, P:neuromuscular process controlling balance, P:protein folding, P:response to amino acid, P:tRNA modification, P:tRNA processing, C:cytoplasm, F:nucleic acid binding, P:response to amino acid stimulus, P:skin development
UniProtAcetylation, Aminoacyl-tRNA synthetase, ATP-binding, Charcot-Marie-Tooth disease, Complete proteome, Cytoplasm, Direct protein sequencing, Disease mutation, Ligase, Metal-binding, Neuropathy, Nucleotide-binding, Phosphoprotein, Polymorphism, Protein biosynthesis, Reference proteome, RNA-binding, tRNA-binding, Ubl conjugation, Zinc
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)2.171.13E-0622252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.178.29E-0423895517

Compile date 09-07-2016© MuScle project