MuScle-logoMuScle - Molecule ID BD310

geneAGER, RAGE
nameAdvanced glycosylation end product-specific receptor precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
RAGE_HUMANQ15109ENSG00000204305|ENSG00000206320|ENSG00000229058|ENSG00000230514|ENSG00000231268|ENSG00000237405|ENSG00000234729177Hs.534342600214

Functions and classifications

GOC:extracellular region, C:integral component of plasma membrane, F:transmembrane signaling receptor activity, P:cell surface receptor signaling pathway, P:induction of positive chemotaxis, P:inflammatory response, P:innate immune response, P:neuron projection development, P:positive regulation of NF-kappaB transcription factor activity, C:membrane, C:axon, C:basal plasma membrane, C:cytoplasm, C:extracellular space, C:integral to plasma membrane, C:neuronal cell body, F:advanced glycation end-product receptor activity, P:brain development, P:calcium ion homeostasis, P:JAK-STAT cascade, P:lung development, P:positive regulation of apoptotic process, P:positive regulation of fibroblast migration, P:positive regulation of inflammatory response, P:positive regulation of smooth muscle cell proliferation, P:response to hyperoxia
UniProt3D-structure, Alternative splicing, Cell membrane, Complete proteome, Disulfide bond, Glycoprotein, Immunoglobulin domain, Inflammatory response, Membrane, Polymorphism, Reference proteome, Repeat, Secreted, Signal, Transmembrane, Transmembrane helix, Receptor
PADBRCP: receptor

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp21216829Homo sapiens8BloodCD4+RRMS_(CD4+) (Multiple sclerosis)4.590.033662721216829
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.813.98E-0422021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.429.15E-0822252466

Compile date 09-07-2016© MuScle project