MuScle-logoMuScle - Molecule ID BD143

geneADSS, ADSS2
nameAdenylosuccinate synthetase 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
PURA2_HUMANP30520ENSG00000035687159Hs.498313103060

Functions and classifications

GOC:cytosol, C:plasma membrane, F:adenylosuccinate synthase activity, F:GTP binding, F:magnesium ion binding, F:phosphate ion binding, P:'de novo' AMP biosynthetic process, P:AMP biosynthetic process, P:aspartate metabolic process, P:cellular response to electrical stimulus, P:GTP catabolic process, P:immune system process, P:IMP metabolic process, P:purine nucleobase metabolic process, P:response to ammonium ion, P:response to purine-containing compound, C:cytoplasm, P:purine nucleotide biosynthetic process
UniProt3D-structure, Complete proteome, Cytoplasm, GTP-binding, Ligase, Magnesium, Metal-binding, Nucleotide-binding, Polymorphism, Purine biosynthesis, Reference proteome, Acetylation
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)0.860.0107159220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)1.886.16E-0320136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)1.710.0217767120136355
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.716.72E-0322252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.733.06E-0222252466

Compile date 09-07-2016© MuScle project