MuScle-logoMuScle - Molecule ID BC687

geneALPL
nameAlkaline phosphatase, tissue-nonspecific isozyme precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
PPBT_HUMANP05186ENSG00000162551249Hs.75431146300, 171760, 241500, 241510

Functions and classifications

GOC:anchored component of membrane, C:extracellular matrix, C:extracellular membrane-bounded organelle, C:extracellular space, C:integral component of membrane, C:plasma membrane, F:alkaline phosphatase activity, F:metal ion binding, F:pyrophosphatase activity, P:cellular response to organic cyclic compound, P:cementum mineralization, P:developmental process involved in reproduction, P:endochondral ossification, P:response to antibiotic, P:response to glucocorticoid, P:response to lipopolysaccharide, P:response to vitamin D, P:skeletal system development, P:dephosphorylation, F:phosphatase activity, C:anchored to membrane, C:integral to membrane, P:response to glucocorticoid stimulus
UniProtAlternative splicing, Biomineralization, Cell membrane, Complete proteome, Direct protein sequencing, Disease mutation, Disulfide bond, Glycoprotein, GPI-anchor, Hydrolase, Lipoprotein, Magnesium, Membrane, Metal-binding, Phosphoprotein, Polymorphism, Reference proteome, Signal, Transmembrane, Zinc
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.677.82E-0420136355
Exp21216829Homo sapiens8BloodCD8+RRMS_(CD8+) (Multiple sclerosis)3.660.0480643821216829
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.881.02E-0222021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.854.15E-0222252466

Compile date 09-07-2016© MuScle project