MuScle-logoMuScle - Molecule ID BC678

geneACP2
nameLysosomal acid phosphatase precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
PPAL_HUMANP11117ENSG0000013457553Hs.532492171650, 200950

Functions and classifications

GOC:integral component of membrane, C:lysosomal lumen, C:lysosomal membrane, C:lysosome, F:acid phosphatase activity, P:lysosome organization, P:skeletal system development, P:dephosphorylation, C:cytoplasmic vesicle, C:integral to membrane, F:phosphoprotein phosphatase activity, P:autophagic cell death, P:response to organic substance
UniProtAlternative splicing, Complete proteome, Direct protein sequencing, Disulfide bond, Glycoprotein, Hydrolase, Lysosome, Membrane, Polymorphism, Reference proteome, Signal, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)1.771.87E-0317467740
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)1.160.0313986420136355
Exp21346816Homo sapiens12Blood MS (Multiple sclerosis)0.670.03173421346816
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_12_month_follow-up) (Multiple sclerosis)1.600.0362349521886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)1.876.81E-0421886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_3_month_follow-up) (Multiple sclerosis)1.720.0023352821886806
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)0.672.13E-0222252466
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)0.742.93E-0222252466

Compile date 09-07-2016© MuScle project