MuScle-logoMuScle - Molecule ID BC673

geneACP5
nameTartrate-resistant acid phosphatase type 5 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
PPA5_HUMANP13686ENSG0000010257554Hs.1211171640, 607944

Functions and classifications

GOC:cytosol, C:integral component of membrane, C:lysosome, F:acid phosphatase activity, F:ferric iron binding, F:ferrous iron binding, P:bone morphogenesis, P:bone resorption, P:defense response to Gram-positive bacterium, P:negative regulation of inflammatory response, P:negative regulation of interleukin-1 beta production, P:negative regulation of interleukin-12 production, P:negative regulation of nitric oxide biosynthetic process, P:negative regulation of superoxide anion generation, P:negative regulation of tumor necrosis factor production, P:response to cytokine, P:response to lipopolysaccharide, P:riboflavin metabolic process, C:integral to membrane, P:response to cytokine stimulus
UniProt3D-structure, Complete proteome, Direct protein sequencing, Disease mutation, Disulfide bond, Glycoprotein, Hydrolase, Iron, Lysosome, Metal-binding, Polymorphism, Reference proteome, Signal
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.841.60E-0220136355
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)0.522.06E-0321886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.651.19E-0522021740
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.530.036546522252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.333.61E-0522252466

Compile date 09-07-2016© MuScle project