MuScle-logoMuScle - Molecule ID BC458

geneAGPAT1, G15
name1-acyl-sn-glycerol-3-phosphate acyltransferase alpha
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
PLCA_HUMANQ99943ENSG00000204310|ENSG00000206324|ENSG00000227642|ENSG00000228892|ENSG00000236873|ENSG00000226467|ENSG0000023575810554Hs.409230603099

Functions and classifications

GOC:endoplasmic reticulum membrane, C:integral component of membrane, F:1-acylglycerol-3-phosphate O-acyltransferase activity, P:CDP-diacylglycerol biosynthetic process, P:energy reserve metabolic process, P:phosphatidic acid biosynthetic process, P:positive regulation of cellular metabolic process, P:positive regulation of cytokine production, P:positive regulation of cytokine-mediated signaling pathway, P:small molecule metabolic process, P:triglyceride biosynthetic process, "F:transferase activity, transferring acyl groups", C:membrane, P:phospholipid biosynthetic process, C:integral to membrane
UniProtAcyltransferase, Complete proteome, Endoplasmic reticulum, Lipid biosynthesis, Lipid metabolism, Membrane, Phospholipid biosynthesis, Phospholipid metabolism, Polymorphism, Reference proteome, Signal, Transferase, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.872.02E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)0.860.022466420136355
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.431.29E-0522252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.151.33E-0223895517
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.152.97E-0223895517

Compile date 09-07-2016© MuScle project