MuScle-logoMuScle - Molecule ID BB791

geneADCYAP1R1
namePituitary adenylate cyclase activating polypeptide type I receptor precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
PACR_HUMANP41586ENSG00000078549117Hs.377783102981

Functions and classifications

GOC:caveola, C:cell surface, C:endosome, C:integral component of plasma membrane, C:neuron projection, C:rough endoplasmic reticulum, C:tight junction, F:neuropeptide binding, F:receptor activity, F:vasoactive intestinal polypeptide receptor activity, P:activation of adenylate cyclase activity, P:activation of phospholipase C activity, P:cAMP-mediated signaling, P:cell differentiation, P:development of primary female sexual characteristics, P:multicellular organismal response to stress, P:negative regulation of cell death, P:neurotrophin TRK receptor signaling pathway, P:positive regulation of calcium ion transport into cytosol, P:positive regulation of inositol phosphate biosynthetic process, P:response to drug, P:response to estradiol, P:response to ethanol, P:spermatogenesis, C:integral component of membrane, F:G-protein coupled receptor activity, C:plasma membrane, P:positive regulation of cAMP biosynthetic process, C:Golgi membrane, C:integral to plasma membrane, F:pituitary adenylate cyclase-activating polypeptide receptor activity, P:nerve growth factor receptor signaling pathway, P:response to estradiol stimulus, C:integral to membrane
UniProt3D-structure, Alternative splicing, Cell membrane, Complete proteome, Developmental protein, Differentiation, Disulfide bond, G-protein coupled receptor, Glycoprotein, Membrane, Receptor, Reference proteome, Signal, Spermatogenesis, Transducer, Transmembrane, Transmembrane helix
PADBRCP: receptor

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50BloodRRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)1.174.07E-0220136355
Exp20136355Homo sapiens50BloodRRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)1.241.91E-0220136355
Exp22491253Homo sapiens7BloodRRMS_(High_Sema4A) (Multiple sclerosis)0.140.0067547122491253

Compile date 09-07-2016© MuScle project