MuScle-logoMuScle - Molecule ID BA102

geneADI1, MTCBP1, HMFT1638
name1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
MTND_HUMANQ9BV57ENSG0000018255155256Hs.502773613400

Functions and classifications

GOC:cytosol, C:Golgi apparatus, C:nucleus, C:plasma membrane, F:acireductone dioxygenase [iron(II)-requiring] activity, F:iron ion binding, P:L-methionine salvage from methylthioadenosine, P:polyamine metabolic process, F:metal ion binding
UniProtAlternative splicing, Amino-acid biosynthesis, Cell membrane, Complete proteome, Cytoplasm, Dioxygenase, Direct protein sequencing, Iron, Membrane, Metal-binding, Methionine biosynthesis, Nucleus, Oxidoreductase, Reference proteome
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.863.02E-0220136355
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)0.673.61E-0221886806
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)0.762.64E-0222252466
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.280.036443722252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.663.07E-0622252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.742.92E-0422252466

Compile date 09-07-2016© MuScle project