MuScle-logoMuScle - Molecule ID B9987

geneABCC6, ara, URG7
nameMultidrug resistance-associated protein 6
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
MRP6_HUMANO95255ENSG00000091262368Hs.442182264800, 603234, 614473, 177850

Functions and classifications

GOC:apical plasma membrane, C:basolateral plasma membrane, C:integral component of membrane, C:lateral plasma membrane, C:plasma membrane, F:ATP binding, F:ATPase activity, coupled to transmembrane movement of substances, P:response to drug, P:visual perception, "C:integral component of membrane, P:ATP catabolic process", F:ATPase activity, coupled to transmembrane movement of substances", C:integral to membrane, "C:integral to membrane
UniProtAlternative splicing, ATP-binding, Cell membrane, Complete proteome, Disease mutation, Glycoprotein, Membrane, Nucleotide-binding, Polymorphism, Reference proteome, Repeat, Sensory transduction, Transmembrane, Transmembrane helix, Transport, Vision, Cyclin, Phosphoprotein
PADBCC: cell cycle (turnover, mitosis, meiosis)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.603.01E-0220136355
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)0.790.008778222252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.763.59E-0322252466

Compile date 09-07-2016© MuScle project