MuScle-logoMuScle - Molecule ID B9984

geneABCC3, MRP3, CMOAT2
nameATP-binding cassette, sub-family C, member 3
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
MRP3_HUMANO15438ENSG000001088468714Hs.463421604323

Functions and classifications

GOC:integral component of plasma membrane, F:ATP binding, F:ATPase activity, coupled to transmembrane movement of substances, F:organic anion transmembrane transporter activity, P:bile acid and bile salt transport, P:bile acid metabolic process, "C:integral component of membrane, P:ATP catabolic process", "C:integral to plasma membrane, "C:integral to membrane, F:ATPase activity, coupled to transmembrane movement of substances"
UniProtAlternative splicing, ATP-binding, Complete proteome, Glycoprotein, Membrane, Nucleotide-binding, Polymorphism, Reference proteome, Repeat, Transmembrane, Transmembrane helix, Transport, Phosphoprotein
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.423.41E-0520136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.551.94E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.691.12E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)0.621.30E-0220136355
Exp20921521Homo sapiens10Blood PPMS_(PRF1_gene_Risk_haplotype) (Multiple sclerosis)0.800.041333720921521
Exp21216829Homo sapiens8BloodCD4+RRMS_(CD4+) (Multiple sclerosis)0.030.004922421216829
Exp21216829Homo sapiens8BloodCD8+RRMS_(CD8+) (Multiple sclerosis)0.300.0263866121216829
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.072.14E-1122252466
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)0.150.0029894922491253
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)0.300.0159165122491253
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)0.300.0328190722491253
Exp22491253Homo sapiens7Blood RRMS_(Low_Sema4A) (Multiple sclerosis)1.880.028259922491253
Exp22491253Homo sapiens7Blood RRMS_(Low_Sema4A) (Multiple sclerosis)5.630.038344422491253

Compile date 09-07-2016© MuScle project