MuScle-logoMuScle - Molecule ID B9983

geneABCC2, CMOAT, CMOAT1
nameCanalicular multispecific organic anion transporter 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
MRP2_HUMANQ92887ENSG000000238391244Hs.368243237500, 601107

Functions and classifications

GOC:apical plasma membrane, C:integral component of plasma membrane, C:intercellular canaliculus, F:ATP binding, F:ATPase activity, coupled to transmembrane movement of substances, F:organic anion transmembrane transporter activity, P:cellular chloride ion homeostasis, P:drug transmembrane transport, P:prostaglandin transport, P:response to arsenic-containing substance, P:response to estrogen, P:response to heat, P:response to methotrexate, P:response to oxidative stress, P:thyroid hormone transport, C:integral to plasma membrane, F:organic anion transmembrane transporter activity"
UniProtATP-binding, Complete proteome, Disease mutation, Glycoprotein, Membrane, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Transmembrane, Transmembrane helix, Transport
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)1.803.69E-0217467740
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_6_month_follow-up) (Multiple sclerosis)1.781.99E-0217467740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.456.72E-0922252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.531.90E-0922252466

Compile date 09-07-2016© MuScle project