MuScle-logoMuScle - Molecule ID B9982

geneABCC1, MRP, MRP1
nameMultidrug resistance-associated protein 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
MRP1_HUMANP33527ENSG000001032224363Hs.391464158343

Functions and classifications

GOC:Golgi apparatus, C:integral component of plasma membrane, C:nucleus, F:ATP binding, F:ATPase activity, coupled to transmembrane movement of substances, P:arachidonic acid metabolic process, P:cobalamin metabolic process, P:leukotriene metabolic process, P:response to drug, "C:integral component of membrane, P:ATP catabolic process", "C:integral component of plasma membrane, F:homoaconitate hydratase activity, P:ATP catabolic process, P:transport", "C:basolateral plasma membrane, C:Golgi apparatus, C:integral to plasma membrane, F:efflux transmembrane transporter activity, F:glutathione S-conjugate-exporting ATPase activity, F:glutathione transmembrane transporter activity, F:lipid-transporting ATPase activity, F:long-chain fatty acid transporter activity, F:sphingolipid transporter activity, F:xenobiotic-transporting ATPase activity, P:cell chemotaxis, P:drug export, P:glutathione transmembrane transport, P:phospholipid efflux, P:plasma membrane long-chain fatty acid transport, P:positive regulation of cell migration, P:response to drug, P:response to oxidative stress", "C:integral to membrane, F:ATPase activity, coupled to transmembrane movement of substances", C:basolateral plasma membrane, C:cytoplasm, P:response to oxidative stress
UniProt3D-structure, Alternative splicing, ATP-binding, Cell membrane, Complete proteome, Glycoprotein, Hydrolase, Membrane, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Transmembrane, Transmembrane helix, Transport
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.101.01E-0222021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.201.40E-0222021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)2.876.15E-1022252466
Exp22491253Homo sapiens7Blood RRMS_(Low_Sema4A) (Multiple sclerosis)1.780.047274722491253

Compile date 09-07-2016© MuScle project