MuScle-logoMuScle - Molecule ID B8967

geneAATK, AATYK, LMR1
nameSerine/threonine-protein kinase LMTK1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
LMTK1_HUMANQ6ZMQ8ENSG000001814099625Hs.514575605276

Functions and classifications

GOC:axonal growth cone, C:endoplasmic reticulum, C:integral component of membrane, C:mitochondrion, C:perinuclear region of cytoplasm, C:recycling endosome, F:ATP binding, F:protein serine/threonine kinase activity, F:protein tyrosine kinase activity, P:brain development, P:negative regulation of axon extension, P:neuron apoptotic process, P:peptidyl-tyrosine autophosphorylation, P:Rab protein signal transduction, C:integral to membrane, P:apoptotic process, P:protein autophosphorylation
UniProtAlternative splicing, ATP-binding, Complete proteome, Cytoplasm, Kinase, Membrane, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome, Serine/threonine-protein kinase, Transferase, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)2.133.66E-0317467740
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)2.566.22E-0317467740
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_6_month_follow-up) (Multiple sclerosis)1.792.50E-0217467740
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_6_month_follow-up) (Multiple sclerosis)2.033.26E-0317467740
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)1.817.33E-0422252466
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)0.670.022608722252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.401.32E-0722252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.291.90E-0222252466

Compile date 09-07-2016© MuScle project