MuScle-logoMuScle - Molecule ID B8127

geneAK2, ADK2
nameAdenylate kinase 2, mitochondrial
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
KAD2_HUMANP54819ENSG00000004455204Hs.470907103020, 267500

Functions and classifications

GOC:cytosol, C:mitochondrial inner membrane, C:mitochondrial intermembrane space, C:sperm mitochondrial sheath, F:adenylate kinase activity, F:ATP binding, P:ADP biosynthetic process, P:AMP metabolic process, P:ATP metabolic process, P:brain development, P:dATP metabolic process, P:liver development, P:nucleobase-containing small molecule interconversion, P:oxidative phosphorylation, P:response to thyroid hormone, F:nucleobase-containing compound kinase activity, P:nucleobase-containing compound metabolic process, P:nucleotide phosphorylation, P:AMP salvage
UniProt3D-structure, Acetylation, Alternative splicing, ATP-binding, Complete proteome, Direct protein sequencing, Disease mutation, Disulfide bond, Kinase, Mitochondrion, Nucleotide-binding, Polymorphism, Reference proteome, Transferase
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)1.122.53E-0220136355
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_24_month_follow-up) (Multiple sclerosis)1.260.030779821886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)1.292.10E-0221886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)1.691.43E-0221886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.155.02E-0322021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.317.47E-0622021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.392.35E-0422021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.463.09E-0622021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.348.85E-0322252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.375.77E-0322252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.431.32E-0422252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.622.30E-0522252466
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)1.710.0418835622491253
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.933.44E-0223895517
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.151.15E-0423895517

Compile date 09-07-2016© MuScle project