MuScle-logoMuScle - Molecule ID B8126

geneAK1
nameAdenylate kinase isoenzyme 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
KAD1_HUMANP00568ENSG00000106992203Hs.175473103000, 612631

Functions and classifications

GOC:cytosol, C:outer dense fiber, C:plasma membrane, C:sperm flagellum, F:adenylate kinase activity, F:ATP binding, F:nucleoside diphosphate kinase activity, P:ATP metabolic process, P:cell cycle arrest, P:nucleobase-containing small molecule interconversion, P:nucleoside triphosphate biosynthetic process, C:cytoplasm, F:nucleobase-containing compound kinase activity, P:nucleobase-containing compound metabolic process, P:nucleoside diphosphate phosphorylation, P:phosphorylation, P:AMP salvage
UniProt3D-structure, Acetylation, ATP-binding, Complete proteome, Cytoplasm, Direct protein sequencing, Disease mutation, Hereditary hemolytic anemia, Kinase, Nucleotide-binding, Polymorphism, Reference proteome, Transferase
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_12_month_follow-up) (Multiple sclerosis)0.460.0093078321886806
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.722.75E-0522252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.662.63E-0322252466

Compile date 09-07-2016© MuScle project