MuScle-logoMuScle - Molecule ID B7986

geneAMICA1, JAML, UNQ722/PRO1387
nameJunctional adhesion molecule-like precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
JAML1_HUMANQ86YT9ENSG00000160593120425Hs.16291609770

Functions and classifications

GOC:integral component of membrane, C:plasma membrane, C:tight junction, F:protein homodimerization activity, P:blood coagulation, P:gamma-delta T cell activation, P:heterophilic cell-cell adhesion, P:monocyte extravasation, P:neutrophil chemotaxis, P:neutrophil extravasation, P:positive regulation of epithelial cell proliferation involved in wound healing, P:regulation of immune response, C:integral to membrane, P:transepithelial transport
UniProtAlternative splicing, Cell adhesion, Cell junction, Cell membrane, Complete proteome, Direct protein sequencing, Disulfide bond, Glycoprotein, Immunity, Immunoglobulin domain, Membrane, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Signal, Transmembrane, Transmembrane helix
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.854.17E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_2_days_follow-up) (Multiple sclerosis)0.822.68E-0220136355
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)0.832.34E-0221886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)0.830.02200721886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.830.023813921886806
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.094.78E-1222252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.101.39E-1222252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.174.63E-0223895517

Compile date 09-07-2016© MuScle project