MuScle-logoMuScle - Molecule ID B7265

geneADHFE1, HMFT2263
nameHydroxyacid-oxoacid transdehydrogenase, mitochondrial precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
HOT_HUMANQ8IWW8ENSG00000147576137872Hs.720023611083

Functions and classifications

GOC:mitochondrial matrix, F:hydroxyacid-oxoacid transhydrogenase activity, F:metal ion binding, P:2-oxoglutarate metabolic process, P:molecular hydrogen transport, F:oxidoreductase activity, C:mitochondrion
UniProtAcetylation, Alternative splicing, Complete proteome, Mitochondrion, Oxidoreductase, Polymorphism, Reference proteome, Transit peptide
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp21346816Homo sapiens12Blood MS (Multiple sclerosis)1.310.02045821346816
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)0.585.39E-0321886806
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)1.442.74E-0222252466
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)0.680.008280122252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.362.41E-0222252466

Compile date 09-07-2016© MuScle project