MuScle-logoMuScle - Molecule ID B7084

geneALAD
nameDelta-aminolevulinic acid dehydratase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
HEM2_HUMANP13716ENSG00000148218210Hs.1227125270, 612740

Functions and classifications

GOC:cytosol, F:lead ion binding, F:porphobilinogen synthase activity, F:zinc ion binding, P:cellular response to interleukin-4, P:heme biosynthetic process, P:protein homooligomerization, P:protoporphyrinogen IX biosynthetic process, P:small molecule metabolic process, F:metal ion binding, P:porphyrin-containing compound biosynthetic process, P:tetrapyrrole biosynthetic process
UniProt3D-structure, Allosteric enzyme, Alternative splicing, Complete proteome, Direct protein sequencing, Disease mutation, Heme biosynthesis, Lyase, Metal-binding, Phosphoprotein, Polymorphism, Porphyrin biosynthesis, Reference proteome, Zinc
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)1.220.0276113920136355
Exp20921521Homo sapiens10Blood PPMS_(PRF1_gene_Risk_haplotype) (Multiple sclerosis)0.770.018402420921521
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.905.07E-0322021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.865.29E-0622252466
Exp22491253Homo sapiens7Blood RRMS_(Low_Sema4A) (Multiple sclerosis)2.730.04951722491253

Compile date 09-07-2016© MuScle project