MuScle-logoMuScle - Molecule ID B6650

geneAGPAT6, GPAT4, UNQ551/PRO1108
nameGlycerol-3-phosphate acyltransferase 4
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
GPAT4_HUMANQ86UL3ENSG00000158669137964Hs.355753608143

Functions and classifications

GOC:endoplasmic reticulum membrane, C:integral component of membrane, F:glycerol-3-phosphate O-acyltransferase activity, P:acyl-CoA metabolic process, P:CDP-diacylglycerol biosynthetic process, P:diacylglycerol metabolic process, P:fatty acid metabolic process, P:glandular epithelial cell maturation, P:lactation, P:phosphatidic acid biosynthetic process, P:phosphatidylcholine biosynthetic process, P:regulation of multicellular organism growth, P:triglyceride biosynthetic process, "C:endoplasmic reticulum, F:transferase activity, transferring acyl groups, P:triglyceride biosynthetic process", "F:transferase activity, transferring acyl groups, P:metabolic process", C:endoplasmic reticulum, C:integral to membrane, "F:transferase activity, transferring acyl groups"
UniProtAcyltransferase, Complete proteome, Direct protein sequencing, Endoplasmic reticulum, Glycoprotein, Lipid biosynthesis, Lipid metabolism, Membrane, Phospholipid biosynthesis, Phospholipid metabolism, Reference proteome, Signal, Transferase, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_12_month_follow-up) (Multiple sclerosis)0.740.0318849221886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)0.655.25E-0321886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.233.51E-0422021740
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)0.733.65E-0222252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.091.71E-0223895517
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.121.61E-0223895517

Compile date 09-07-2016© MuScle project