MuScle-logoMuScle - Molecule ID B4147

geneAMD1, AMD
nameAdenosylmethionine decarboxylase 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
DCAM_HUMANP17707ENSG00000123505262Hs.159118180980

Functions and classifications

GOC:cytosol, F:adenosylmethionine decarboxylase activity, P:S-adenosylmethioninamine biosynthetic process, P:small molecule metabolic process, P:spermidine biosynthetic process, P:spermine biosynthetic process
UniProt3D-structure, Alternative splicing, Autocatalytic cleavage, Complete proteome, Decarboxylase, Direct protein sequencing, Lyase, Phosphoprotein, Polyamine biosynthesis, Pyruvate, Reference proteome, S-adenosyl-L-methionine, Schiff base, Spermidine biosynthesis, Zymogen
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)1.371.10E-0221886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.092.14E-0222021740
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)0.780.047205222252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)3.036.59E-0922252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)3.433.21E-1122252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.771.32E-0323895517
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.834.74E-0323895517

Compile date 09-07-2016© MuScle project