MuScle-logoMuScle - Molecule ID B1605

geneBRD7, BP75, CELTIX1
nameBromodomain-containing protein 7
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
BRD7_HUMANQ9NPI1ENSG0000016616429117Hs.437894

Functions and classifications

GOC:cytoplasm, C:nucleus, F:histone acetyl-lysine binding, F:transcription coactivator activity, F:transcription corepressor activity, F:transcription factor binding, F:transcription regulatory region DNA binding, P:cell cycle, P:negative regulation of cell proliferation, P:negative regulation of G1/S transition of mitotic cell cycle, P:negative regulation of transcription, DNA-templated, P:positive regulation of histone acetylation, P:positive regulation of transcription, DNA-templated, P:regulation of transcription from RNA polymerase II promoter, P:transcription, DNA-templated, P:Wnt signaling pathway, P:negative regulation of transcription, DNA-dependent, P:positive regulation of transcription, DNA-dependent, P:transcription, DNA-dependent, P:Wnt receptor signaling pathway", P:regulation of RNA biosynthetic process
UniProt3D-structure, Alternative splicing, Bromodomain, Cell cycle, Coiled coil, Complete proteome, Nucleus, Phosphoprotein, Reference proteome, Transcription, Transcription regulation, Tumor suppressor, Wnt signaling pathway
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)1.243.59E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)1.430.0311692820136355
Exp20921521Homo sapiens10Blood PPMS_(PRF1_gene_Risk_haplotype) (Multiple sclerosis)0.750.018651520921521
Exp20921521Homo sapiens10Blood PPMS_(PRF1_gene_Risk_haplotype) (Multiple sclerosis)0.790.041092720921521
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.501.58E-0622021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.751.80E-0322021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.903.10E-0222021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.349.98E-0522021740
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.300.018651422252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.183.69E-0222252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.771.76E-0323895517

Compile date 09-07-2016© MuScle project