MuScle-logoMuScle - Molecule ID B1479

geneBFAR, BAR, RNF47
nameBifunctional apoptosis regulator
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
BFAR_HUMANQ9NZS9ENSG0000010342951283Hs.435556

Functions and classifications

GOC:endoplasmic reticulum membrane, C:integral component of plasma membrane, F:structural molecule activity, F:zinc ion binding, P:apoptotic process, P:negative regulation of apoptotic process, C:integral to plasma membrane, F:metal ion binding
UniProtApoptosis, Complete proteome, Endoplasmic reticulum, Glycoprotein, Membrane, Metal-binding, Polymorphism, Reference proteome, Transmembrane, Transmembrane helix, Zinc, Zinc-finger
PADBMOD: modulator, regulator

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)0.661.87E-0217467740
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.790.0003214420136355
Exp20921521Homo sapiens10Blood PPMS_(PRF1_gene_Risk_haplotype) (Multiple sclerosis)0.530.030563820921521
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.274.33E-0522021740
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.190.009137622252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.562.85E-0422252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.234.62E-0523895517

Compile date 09-07-2016© MuScle project