MuScle-logoMuScle - Molecule ID B1408

geneBAZ1B, WBSC10, WBSCR10
nameTyrosine-protein kinase BAZ1B
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BAZ1B_HUMANQ9UIG0ENSG00000009954|ENSG000002626949031Hs.743372605681

Functions and classifications

GOC:centromeric heterochromatin, C:condensed chromosome, C:WINAC complex, F:ATP binding, F:chromatin binding, F:histone acetyl-lysine binding, F:histone kinase activity, F:non-membrane spanning protein tyrosine kinase activity, F:protein complex scaffold, F:protein tyrosine kinase activity, F:vitamin D receptor activator activity, F:zinc ion binding, P:ATP-dependent chromatin remodeling, P:chromatin-mediated maintenance of transcription, P:DNA replication-dependent nucleosome disassembly, P:double-strand break repair, P:heart morphogenesis, P:transcription, DNA-templated, F:metal ion binding, P:transcription, DNA-dependent"
UniProt3D-structure, Alternative splicing, ATP-binding, Bromodomain, Coiled coil, Complete proteome, DNA damage, Kinase, Metal-binding, Nucleotide-binding, Nucleus, Phosphoprotein, Reference proteome, Transcription, Transcription regulation, Transferase, Tyrosine-protein kinase, Williams-Beuren syndrome, Zinc, Zinc-finger
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)2.111.86E-0417467740
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_6_month_follow-up) (Multiple sclerosis)1.752.38E-0317467740
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)0.880.0194092820136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)1.670.02084120136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_2_days_follow-up) (Multiple sclerosis)1.740.0168524120136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.760.0305395820136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.900.0473455220136355
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.757.21E-0322021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.272.31E-0422021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.441.31E-0422252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.196.44E-0423895517

Compile date 09-07-2016© MuScle project