MuScle-logoMuScle - Molecule ID B1318

geneB2M, HDCMA22P
nameBeta-2-microglobulin precursor
speciesHomo sapiens

Molecule reference

B2MG_HUMANP61769ENSG00000166710567Hs.534255109700, 241600

Functions and classifications

GOC:early endosome lumen, C:early endosome membrane, C:endoplasmic reticulum lumen, C:ER to Golgi transport vesicle membrane, C:external side of plasma membrane, C:extracellular region, C:extracellular space, C:Golgi membrane, C:MHC class I protein complex, C:phagocytic vesicle membrane, C:plasma membrane, P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent, P:antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent, P:interferon-gamma-mediated signaling pathway, P:positive regulation of T cell mediated cytotoxicity, P:protein refolding, P:regulation of defense response to virus by virus, P:regulation of immune response, P:response to cadmium ion, P:response to drug, P:response to molecule of bacterial origin, P:T cell differentiation in thymus, P:viral process, P:antigen processing and presentation of peptide antigen via MHC class I, P:immune response, "C:external side of plasma membrane, P:T cell differentiation in thymus", C:Golgi apparatus, P:viral reproduction"
UniProt3D-structure, Amyloid, Amyloidosis, Complete proteome, Direct protein sequencing, Disease mutation, Disulfide bond, Glycation, Glycoprotein, Immunity, Immunoglobulin domain, MHC I, Pyrrolidone carboxylic acid, Reference proteome, Secreted, Signal
PADBMHC: major histocompatibility complex component/protein cluster (MHC, HLA)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)1.249.49E-0321886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.362.82E-0622021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.925.20E-0322021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.043.08E-0222021740
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)1.441.19E-0222252466
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)0.480.011724122252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.389.97E-0522252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.459.33E-1122252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.154.52E-0223895517

Compile date 09-07-2016© MuScle project