MuScle-logoMuScle - Molecule ID B1271

geneADAMTS7
nameADAM metallopeptidase with Thrombospondin type 1 motif, 7, preproprotein
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATS7_HUMANQ9UKP4ENSG0000013637811173Hs.16441605009

Functions and classifications

GOC:cell surface, C:proteinaceous extracellular matrix, F:metalloendopeptidase activity, F:zinc ion binding, P:cellular response to BMP stimulus, P:cellular response to interleukin-1, P:cellular response to tumor necrosis factor, P:negative regulation of chondrocyte differentiation, P:proteolysis involved in cellular protein catabolic process, C:extracellular region, P:integrin-mediated signaling pathway, P:proteolysis, F:peptidase activity, P:metabolic process, F:metal ion binding, F:metallopeptidase activity
UniProtCleavage on pair of basic residues, Complete proteome, Direct protein sequencing, Disulfide bond, Extracellular matrix, Glycoprotein, Hydrolase, Metal-binding, Metalloprotease, Polymorphism, Protease, Proteoglycan, Reference proteome, Repeat, Secreted, Signal, Zinc, Zymogen, Integrin
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.330.04037122252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.707.21E-0322252466
Exp22491253Homo sapiens7Blood RRMS_(Low_Sema4A) (Multiple sclerosis)2.160.028387222491253

Compile date 09-07-2016© MuScle project