MuScle-logoMuScle - Molecule ID B1270

geneADAMTS6
nameADAMTS-6 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATS6_HUMANQ9UKP5ENSG0000004919211174Hs.482291605008

Functions and classifications

GOC:proteinaceous extracellular matrix, F:metalloendopeptidase activity, F:metallopeptidase activity, F:zinc ion binding, P:proteolysis, F:peptidase activity, P:metabolic process, F:metal ion binding
UniProtAlternative splicing, Cleavage on pair of basic residues, Complete proteome, Disulfide bond, Extracellular matrix, Glycoprotein, Hydrolase, Metal-binding, Metalloprotease, Protease, Reference proteome, Repeat, Secreted, Signal, Zinc, Zymogen
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)1.701.41E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.720.028573820136355
Exp21216829Homo sapiens8BloodCD8+RRMS_(CD8+) (Multiple sclerosis)0.220.007209321216829
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.861.70E-0322021740
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)2.030.0426112822491253
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.916.23E-0423895517

Compile date 09-07-2016© MuScle project