MuScle-logoMuScle - Molecule ID B1268

geneADAMTS4, UNQ769/PRO1563, UNQ769
nameA disintegrin and metalloproteinase with thrombospondin motifs 4
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATS4_HUMANO75173ENSG000001588599507Hs.211604603876

Functions and classifications

GOC:extracellular space, C:proteinaceous extracellular matrix, F:metalloendopeptidase activity, F:metallopeptidase activity, F:zinc ion binding, P:proteolysis, P:skeletal system development, F:metal ion binding
UniProt3D-structure, Cleavage on pair of basic residues, Complete proteome, Direct protein sequencing, Disulfide bond, Extracellular matrix, Glycoprotein, Hydrolase, Metal-binding, Metalloprotease, Polymorphism, Protease, Reference proteome, Secreted, Signal, Zinc, Zymogen
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)1.721.22E-0217467740
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)1.290.01078721886806
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.661.63E-0522252466

Compile date 09-07-2016© MuScle project