MuScle-logoMuScle - Molecule ID B1267

geneADAMTS3
nameA disintegrin and metalloproteinase with thrombospondin motifs 3
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATS3_HUMANO15072ENSG000001561409508Hs.590919605011

Functions and classifications

GOC:proteinaceous extracellular matrix, F:heparin binding, F:metalloendopeptidase activity, F:zinc ion binding, P:collagen catabolic process, P:collagen fibril organization, P:protein processing, P:proteolysis, F:peptidase activity, P:integrin-mediated signaling pathway, F:metal ion binding
UniProtCleavage on pair of basic residues, Complete proteome, Disulfide bond, Extracellular matrix, Glycoprotein, Heparin-binding, Hydrolase, Metal-binding, Metalloprotease, Polymorphism, Protease, Reference proteome, Repeat, Secreted, Signal, Zinc, Zymogen, Integrin
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)1.555.92E-0317467740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.221.80E-0322252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.522.04E-0522252466

Compile date 09-07-2016© MuScle project