MuScle-logoMuScle - Molecule ID B1265

geneADAMTS2, PCINP, PCPNI
nameADAMTS-2 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATS2_HUMANO95450ENSG000000871169509Hs.23871225410, 604539

Functions and classifications

GOC:extracellular region, C:proteinaceous extracellular matrix, F:metalloendopeptidase activity, F:zinc ion binding, P:collagen catabolic process, P:collagen fibril organization, P:extracellular matrix organization, P:lung development, P:protein processing, P:proteolysis, P:skin development, P:spermatogenesis, F:metal ion binding
UniProtAlternative splicing, Collagen degradation, Complete proteome, Disulfide bond, Ehlers-Danlos syndrome, Extracellular matrix, Glycoprotein, Hydrolase, Metal-binding, Metalloprotease, Polymorphism, Protease, Reference proteome, Repeat, Secreted, Signal, Zinc, Zymogen
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)1.681.15E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_2_days_follow-up) (Multiple sclerosis)2.925.73E-0720136355
Exp21216829Homo sapiens8BloodCD4+RRMS_(CD4+) (Multiple sclerosis)0.280.048841221216829
Exp21216829Homo sapiens8BloodCD4+RRMS_(CD4+) (Multiple sclerosis)26.720.030622621216829
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.713.54E-0522252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.898.98E-0322252466
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)0.200.0426011522491253

Compile date 09-07-2016© MuScle project