MuScle-logoMuScle - Molecule ID B1257

geneADAMTS12, UNQ1918/PRO4389, UNQ1918
nameADAM metallopeptidase with thrombospondin type 1 motif, 1, preproprotein
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATS12_HUMANP58397ENSG0000015138881792Hs.12680606184

Functions and classifications

GOC:proteinaceous extracellular matrix, F:metalloendopeptidase activity, F:zinc ion binding, P:proteolysis, F:metal ion binding
UniProtAlternative splicing, Cleavage on pair of basic residues, Complete proteome, Disulfide bond, Extracellular matrix, Glycoprotein, Hydrolase, Metal-binding, Metalloprotease, Polymorphism, Protease, Reference proteome, Repeat, Secreted, Signal, Zinc, Zymogen, Phosphoprotein
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)1.390.0375565920136355
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.944.78E-0222021740
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.934.40E-0223895517

Compile date 09-07-2016© MuScle project