MuScle-logoMuScle - Molecule ID B1255

geneADAMTS1, METH1
nameADAMTS-1 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATS1_HUMANQ9UHI8ENSG000001547349510Hs.643357605174

Functions and classifications

GOC:basement membrane, C:cytoplasmic vesicle, F:heparin binding, F:metalloendopeptidase activity, F:metallopeptidase activity, F:zinc ion binding, P:heart trabecula formation, P:integrin-mediated signaling pathway, P:kidney development, P:negative regulation of cell proliferation, P:ovulation from ovarian follicle, P:proteolysis, C:proteinaceous extracellular matrix, F:metal ion binding
UniProt3D-structure, Calcium, Cleavage on pair of basic residues, Complete proteome, Disulfide bond, Extracellular matrix, Glycoprotein, Heparin-binding, Hydrolase, Metal-binding, Metalloprotease, Polymorphism, Protease, Reference proteome, Repeat, Secreted, Signal, Zinc, Zymogen, Integrin
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.672.86E-0222021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.372.19E-0422252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.801.46E-0622252466

Compile date 09-07-2016© MuScle project