MuScle-logoMuScle - Molecule ID B1207

geneATG7, APG7L, GSA7
nameAutophagy-related protein 7
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATG7_HUMANO95352ENSG0000019754810533Hs.38032608760

Functions and classifications

GOC:axoneme, C:pre-autophagosomal structure, F:APG12 activating enzyme activity, F:protein homodimerization activity, F:ubiquitin activating enzyme activity, P:adult walking behavior, P:autophagy, P:cardiac muscle cell development, P:cellular amino acid metabolic process, P:central nervous system neuron axonogenesis, P:cerebellar Purkinje cell layer development, P:cerebral cortex development, P:liver development, P:membrane fusion, P:negative regulation of apoptotic process, P:neurological system process, P:organelle organization, P:positive regulation of macroautophagy, P:positive regulation of protein modification process, P:post-embryonic development, P:protein catabolic process, P:protein lipidation, P:protein modification by small protein conjugation, P:protein transport, P:pyramidal neuron development, P:regulation of protein ubiquitination, P:response to starvation, C:cytoplasm, F:catalytic activity, F:nucleotide binding, P:cellular membrane fusion, P:metabolic process, P:cellular membrane organization
UniProtAcetylation, Alternative splicing, Autophagy, Complete proteome, Cytoplasm, Polymorphism, Protein transport, Reference proteome, Transport, Ubl conjugation pathway
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)1.150.0060855920136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)1.160.0190063820136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)1.180.0041058920136355
Exp20921521Homo sapiens10Blood PPMS_(PRF1_gene_Risk_haplotype) (Multiple sclerosis)0.630.025818420921521
Exp21216829Homo sapiens8BloodCD8+RRMS_(CD8+) (Multiple sclerosis)0.260.0198790721216829
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.292.21E-0422021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.488.52E-0622021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.321.34E-1022252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.517.82E-0822252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.134.28E-0323895517

Compile date 09-07-2016© MuScle project