MuScle-logoMuScle - Molecule ID B1157

geneATP2B1, PMCA1
namePlasma membrane calcium-transporting ATPase 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AT2B1_HUMANP20020ENSG00000070961490Hs.506276108731

Functions and classifications

GOC:integral component of plasma membrane, F:ATP binding, F:calcium-transporting ATPase activity, F:metal ion binding, P:blood coagulation, P:ATP catabolic process, P:calcium ion transmembrane transport, C:integral component of membrane, F:cation-transporting ATPase activity, P:ion transmembrane transport, C:integral to plasma membrane, P:ATP biosynthetic process, "C:integral to membrane, F:ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism, P:cation transport", C:integral to membrane
UniProtAcetylation, Alternative splicing, ATP-binding, Calcium, Calcium transport, Calmodulin-binding, Cell membrane, Complete proteome, Hydrolase, Ion transport, Magnesium, Membrane, Metal-binding, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome, Transmembrane, Transmembrane helix, Transport
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20921521Homo sapiens10Blood PPMS_(PRF1_gene_Risk_haplotype) (Multiple sclerosis)0.580.04925420921521
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.162.21E-0222021740
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)1.710.044587522491253
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.742.47E-0323895517

Compile date 09-07-2016© MuScle project