MuScle-logoMuScle - Molecule ID B1132

geneASXL2, ASXH2
namePolycomb group protein
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ASXL2_HUMANQ76L83ENSG0000014397055252Hs.119815612991

Functions and classifications

GOC:nucleus, F:DNA binding, F:metal ion binding, F:peroxisome proliferator activated receptor binding, P:positive regulation of fat cell differentiation, P:positive regulation of peroxisome proliferator activated receptor signaling pathway, P:positive regulation of transcription from RNA polymerase II promoter, P:transcription, DNA-templated, "F:DNA binding, P:regulation of transcription, DNA-templated, P:transcription, DNA-dependent"
UniProtAlternative splicing, Chromosomal rearrangement, Complete proteome, Metal-binding, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Repressor, Transcription, Transcription regulation, Zinc, Zinc-finger
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)1.163.86E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.760.0436927120136355
Exp21216829Homo sapiens8BloodCD8+RRMS_(CD8+) (Multiple sclerosis)0.330.0048132921216829
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)1.293.99E-0221886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)1.502.84E-0221886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.153.34E-0222021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.476.83E-0522021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.482.14E-0622021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.653.12E-0422252466
Exp22491253Homo sapiens7Blood RRMS_(Low_Sema4A) (Multiple sclerosis)1.890.01334822491253
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.495.53E-0723895517

Compile date 09-07-2016© MuScle project