MuScle-logoMuScle - Molecule ID B1124

geneASS1, ASS
nameArgininosuccinate synthase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ASSY_HUMANP00966ENSG00000130707445Hs.160786215700, 603470

Functions and classifications

GOC:cell body fiber, C:cytosol, C:endoplasmic reticulum, C:lysosome, C:mitochondrial outer membrane, C:nucleus, C:perikaryon, F:argininosuccinate synthase activity, F:ATP binding, F:toxic substance binding, P:acute-phase response, P:aging, P:arginine biosynthetic process, P:argininosuccinate metabolic process, P:cellular response to amine stimulus, P:cellular response to amino acid stimulus, P:cellular response to ammonium ion, P:cellular response to cAMP, P:cellular response to dexamethasone stimulus, P:cellular response to glucagon stimulus, P:cellular response to interferon-gamma, P:cellular response to lipopolysaccharide, P:cellular response to oleic acid, P:cellular response to tumor necrosis factor, P:diaphragm development, P:kidney development, P:liver development, P:midgut development, P:response to drug, P:response to estradiol, P:response to growth hormone, P:response to mycotoxin, P:response to nutrient, P:response to zinc ion, P:urea cycle, F:toxin binding, P:response to estradiol stimulus, P:response to growth hormone stimulus, C:cytoplasm
UniProt3D-structure, Amino-acid biosynthesis, Arginine biosynthesis, ATP-binding, Complete proteome, Direct protein sequencing, Disease mutation, Ligase, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome, Urea cycle
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_6_month_follow-up) (Multiple sclerosis)2.752.50E-0217467740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)3.161.39E-0822252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.084.98E-0223895517
Exp24850724Homo sapiens12Blood CIS (Multiple sclerosis)1.830.026607824850724

Compile date 09-07-2016© MuScle project