MuScle-logoMuScle - Molecule ID B1099

geneACCN2, ASIC1, BNAC2
nameAmiloride-sensitive cation channel 2, neuronal
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ASIC1_HUMANP78348ENSG0000011088141Hs.274361602866

Functions and classifications

GOC:cell surface, C:integral component of plasma membrane, C:synapse, F:ligand-gated sodium channel activity, P:associative learning, P:calcium ion transmembrane transport, P:memory, P:negative regulation of neurotransmitter secretion, P:regulation of membrane potential, P:response to acid, P:response to pH, P:signal transduction, C:integral component of membrane, P:sodium ion transmembrane transport, F:sodium channel activity, C:integral to membrane, C:integral to plasma membrane
UniProtAlternative splicing, Calcium, Calcium transport, Cell membrane, Complete proteome, Disulfide bond, Glycoprotein, Ion channel, Ion transport, Membrane, Phosphoprotein, Reference proteome, Sodium, Sodium channel, Sodium transport, Transmembrane, Transmembrane helix, Transport
PADBCNL: channel

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.566.29E-0320136355
Exp21216829Homo sapiens8BloodCD8+RRMS_(CD8+) (Multiple sclerosis)0.140.0133050721216829
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.755.67E-0422252466

Compile date 09-07-2016© MuScle project