MuScle-logoMuScle - Molecule ID B1019

geneACTR3, ARP3
nameActin-like protein 3
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARP3_HUMANP61158ENSG0000011509110096Hs.433512604222

Functions and classifications

GOC:Arp2/3 protein complex, C:cytosol, C:excitatory synapse, C:Golgi membrane, C:hemidesmosome, C:lamellipodium, C:podosome, F:ATP binding, P:asymmetric cell division, P:cellular component movement, P:cilium morphogenesis, P:establishment or maintenance of cell polarity, P:Fc-gamma receptor signaling pathway involved in phagocytosis, P:innate immune response, P:meiotic cytokinesis, P:positive regulation of actin filament polymerization, P:positive regulation of dendrite morphogenesis, P:positive regulation of filopodium assembly, P:positive regulation of lamellipodium assembly, P:positive regulation of neuron differentiation, P:regulation of myosin II filament organization, P:response to antibiotic, P:response to carbohydrate, P:spindle localization, C:actin filament, P:cytokinesis after meiosis, P:meiotic cell cycle, P:response to carbohydrate stimulus, C:cytoskeleton, P:regulation of actin filament polymerization
UniProtAcetylation, Actin-binding, ATP-binding, Cell projection, Cilium biogenesis/degradation, Complete proteome, Cytoplasm, Cytoskeleton, Direct protein sequencing, Nucleotide-binding, Reference proteome, Phosphoprotein
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)1.548.79E-0321886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)1.370.01319521886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)1.330.016824521886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.861.64E-0222021740
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.270.014493122252466
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.310.024374622252466
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.330.019033122252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.403.20E-0822252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.412.47E-0722252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.472.00E-0722252466

Compile date 09-07-2016© MuScle project