MuScle-logoMuScle - Molecule ID B1017

geneACTR2, ARP2
nameActin-like protein 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARP2_HUMANP61160ENSG0000013807110097Hs.643727604221

Functions and classifications

GOC:actin cap, C:Arp2/3 protein complex, C:cell projection, C:cytosol, F:ATP binding, P:Arp2/3 complex-mediated actin nucleation, P:asymmetric cell division, P:cellular component movement, P:cytoplasmic transport, P:establishment or maintenance of cell polarity, P:Fc-gamma receptor signaling pathway involved in phagocytosis, P:innate immune response, P:meiotic cytokinesis, P:spindle localization, C:cytoplasm, P:actin cytoskeleton organization, P:cytokinesis after meiosis, P:meiotic cell cycle
UniProtAcetylation, Actin-binding, Alternative splicing, ATP-binding, Cell projection, Complete proteome, Cytoplasm, Cytoskeleton, Direct protein sequencing, Nucleotide-binding, Reference proteome
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)1.506.41E-0317467740
Exp20921521Homo sapiens10Blood PPMS_(PRF1_gene_Risk_haplotype) (Multiple sclerosis)0.340.020329920921521
Exp20921521Homo sapiens10Blood PPMS_(PRF1_gene_Risk_haplotype) (Multiple sclerosis)0.500.040999320921521
Exp20921521Homo sapiens10Blood PPMS_(PRF1_gene_Risk_haplotype) (Multiple sclerosis)0.550.037161520921521
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)1.611.43E-0221886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)2.133.59E-0321886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)2.414.89E-0321886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_3_month_follow-up) (Multiple sclerosis)1.610.0373421221886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.113.35E-0222021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.201.47E-0322021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.304.95E-0322021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.314.63E-1022252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.412.52E-0922252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.579.43E-0422252466

Compile date 09-07-2016© MuScle project