MuScle-logoMuScle - Molecule ID B0937

geneARHGEF40, SOLO
nameRho guanine nucleotide exchange factor 40
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARH40_HUMANQ8TER5ENSG0000016580155701Hs.35125610018

Functions and classifications

GOC:cytoplasm, F:Rho guanyl-nucleotide exchange factor activity, P:regulation of Rho GTPase activity, F:phospholipid binding, P:regulation of Rho protein signal transduction, C:intracellular
UniProtAlternative splicing, Coiled coil, Complete proteome, Cytoplasm, Guanine-nucleotide releasing factor, Phosphoprotein, Polymorphism, Reference proteome
PADBMOD: modulator, regulator

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.763.82E-0320136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.813.46E-0320136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)1.190.0271498220136355
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)0.790.03051321886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.623.07E-0322021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.881.25E-0222021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.722.62E-0222252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.934.40E-0223895517

Compile date 09-07-2016© MuScle project