MuScle-logoMuScle - Molecule ID B0929

geneARHGEF10L, GRINCHGEF
nameRho guanine nucleotide exchange factor (GEF) 10-like
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARGAL_HUMANQ9HCE6ENSG0000007496455160Hs.443460612494

Functions and classifications

GOC:cytoplasm, F:Rho guanyl-nucleotide exchange factor activity, P:regulation of Rho GTPase activity, C:cytosol, F:Rho GTPase activator activity, P:positive regulation of stress fiber assembly, P:SREBP signaling pathway, P:regulation of Rho protein signal transduction, C:intracellular
UniProtAlternative splicing, Complete proteome, Cytoplasm, Guanine-nucleotide releasing factor, Phosphoprotein, Polymorphism, Reference proteome
PADBMOD: modulator, regulator

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)1.353.98E-0221886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.346.99E-0422021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.051.17E-1422252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.122.60E-1122252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.931.60E-0223895517

Compile date 09-07-2016© MuScle project